College fantasy football managers face a critical test in Week 6 as 11 Power Four teams enter their bye weeks ahead of the Columbus Day holiday weekend, Yahoo Sports reported. With a significant portion of rosters sidelined, managers are forced to identify dependable substitutes and exploit favorable matchups across the national schedule.
Top quarterback and running back starts
Under center, Notre Dame quarterback CJ Carr presents one of the premier starting opportunities of the week against Stanford, according to Yahoo Sports. Carr slipped down summer drafts because of perceived limits on rushing volume, but he has delivered at least three touchdown passes in four of his first five contests while scoring a short-yardage touchdown in three consecutive games. Carr now faces a Cardinal defense that sits 132nd in passing success rate and yields 7.7 yards per dropback.
Arizona quarterback Noah Fifita also enters a favorable matchup against West Virginia. Fifita carries a 73 percent completion rate and a 52 percent passing success rate into a matchup against a Mountaineers defense that ranks 107th in defensive SP+ and yields 20 or more yards on 10 percent of snaps, Yahoo Sports reported. Meanwhile, Ohio State passer Julian Sayin has reached at least 25 fantasy points in three of five games and faces a Maryland unit that has surrendered 137 points over its past three games.
At running back, Virginia Tech newcomer Jeffrey Overton Jr. is positioned for heavy volume at California. Overton has averaged 5.9 yards per carry and 4.5 yards after contact, surpassing Marcellous Hawkins for backfield duties, according to Yahoo Sports. Overton meets a Golden Bears front allowing 187 rushing yards per contest, which ranks 121st nationally.
Other prominent running back options include Indiana rusher Turbo Richard, who compiled 204 yards on 13 touches against Nebraska after recovering from an earlier injury, and BYU back Journee Tonga. Tonga is stepping into the lead role in Provo with teammate LJ Martin expected to miss one month because of a lower leg injury. Syracuse running back Tylik Hill also offers strong upside against Virginia after recording a 57 percent success rate this season, Yahoo Sports noted.
Receiving options and players to bench
In the passing game, Minnesota wideout Javon Tracy has drawn strong interest ahead of a matchup with Purdue. The Boilermakers have allowed first downs on 67 percent of completed passes and permitted 24 percent of completions to gain 20 yards or more, according to Yahoo Sports. Tracy has collected at least five catches in nearly every contest, benefiting from quarterback Drake Lindsey. At tight end, Oregon’s Jamari Johnson has generated 176 receiving yards across two games and faces a UCLA defense that sits 133rd in yards allowed per successful dropback.
Conversely, fantasy managers are advised to bench several notable contributors facing difficult defensive tests. Oklahoma quarterback John Mateer enters the rivalry showdown against Texas having failed to reach 20 fantasy points this season, while the Sooners rank 121st nationally by going three-and-out on 34 percent of possessions, Yahoo Sports reported. Texas counters with a pass defense allowing a 33 percent success rate.
Other recommended sits include Washington quarterback Demond Williams against an Iowa defense forcing three-and-outs on 45 percent of drives, and South Carolina wide receiver Nyck Harbor against Florida. Harbor is catching only 40 percent of targets with an average depth of target of six yards, according to Yahoo Sports. Nebraska running back Mekhi Nelson and Cal pass catchers Ian Strong and Mason Mini also project for reduced roles.
Fantasy managers will soon see whether these depth-chart shifts and defensive vulnerabilities hold true as kickoff approaches across the country this weekend.



